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Research published in the Journal of Gerontology shows that muscle carnitine concentrations decline by ~510% per decade after age 30, resulting in slower fat oxidation and reduced energy availability during caloric deficits (Soop et al., 2001)

J Clin Endocrinol Metab (2001) 86:50836.10.1210/jcem.86.10.8098 37 FuscoABianchiAManciniAMilardiDGiampietroACiminoVet alEffects of ghrelin administration on endocrine and metabolic parameters in obese women with polycystic ovary syndrome